| I: | Gene therapy involves the introduction of a functional gene into the cells of an individual to treat genetic disorders. |
| II: | RNA interference (RNAi) is a technique used to silence specific genes by degrading their structural genes located on template DNA. |
| III: | Transgenic organisms are those that have been genetically modified to express desirable traits. |
| 1. | Decrease their susceptibility to diseases for research purposes. |
| 2. | Produce substances that are useful for medical applications. |
| 3. | Decrease their growth rate to study developmental processes. |
| 4. | Reproduce through asexual means, increasing population uniformity. |
| Assertion (A): | The milk produced by the first transgenic cow, Rosie, was nutritionally a more balanced product for human babies than natural cow-milk. |
| Reason (R): | The first transgenic cow, Rosie, produced human lactose-enriched milk. |
| 1. | Both (A) and (R) are True and (R) correctly explains (A). |
| 2. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 3. | (A) is True; (R) is False |
| 4. | Both (A) and (R) are False |
| (a) | Transgenic animals can be used to produce biologically active human proteins like α-1-antitrypsin for therapeutic purposes. |
| (b) | Transgenic animals are mainly used to test the safety of recombinant insulin for humans. |
| 1. | Only (a) is correct | 2. | Only (b) is correct |
| 3. | Both (a) and (b) are correct | 4. | Both (a) and (b) are incorrect |