Human insulin produced through recombinant DNA technology:
1. Has a higher risk of causing allergies compared to pig insulin.
2. Is exactly the same as insulin produced in the human pancreas.
3. Is produced by inserting the human insulin gene into bacteria.
4. Requires human cells for production.
Subtopic:  Med Applications & Humulin |
 58%
Level 3: 35%-60%
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Statements related to human Insulin are given below.
Which statement(s) is/are correct about genetically engineered Insulin?
(a) Pro-hormone insulin contain extra stretch of C-peptide
(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.
(c) Insulin used for treating Diabetes was extracted from Cattles and Pigs.
(d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone.
(e) Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:
1. (c), (d) and (e) only 2. (a), (b) and (d) only
3. (b) only 4. (c) and (d) only
Subtopic:  Med Applications & Humulin |
Level 3: 35%-60%
NEET - 2022
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Consider the given two statements:
Assertion(A): The main challenge for production of insulin using rDNA techniques was
getting insulin assembled into a mature form.
Reason (R): Insulin consists of two short polypeptide chains: chain A and chain B, that
are linked together by disulphide bridges.
 
1. Both (A) and (R) are True and (R) correctly explains (A).
2. Both (A) and (R) are True but (R) does not correctly explain (A).
3. (A) is True; (R) is False
4. Both (A) and (R) are False
Subtopic:  Med Applications & Humulin |
 59%
Level 3: 35%-60%
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Consider the given two statements:
Assertion(A): Insulin isolated from other cattle or pigs is not as effective as that secreted by the human body itself.
Reason (R): Insulin isolated from other cattle or pigs will elicit an immune response in the human body
 
1. Both (A) and (R) are True and (R) correctly explains (A).
2. Both (A) and (R) are True but (R) does not correctly explain (A).
3. (A) is True; (R) is False
4. Both (A) and (R) are False
Subtopic:  Med Applications & Humulin |
Level 4: Below 35%
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How many of the given statements regarding insulin are correct?
I: All diabetics require insulin from the very beginning.
II: Insulin can be given orally to diabetics.
III. Insulin extracted from pancreas of slaughtered cattle and pigs caused some patients to develop allergy.
IV. Recombinant insulin was first prepared by Indian pharmaceutical giant Ranbaxy.
V. The two polypeptide chains in the final structure of Insulin are joined by disulfide bonds.
VI. DNA sequences corresponding to A  and B chains of human insulin were introduced in plasmids of E.coli to produce insulin chains for preparing recombinant insulin.
 
1. 2 2. 3
3. 4 4. 5
Subtopic:  Med Applications & Humulin |
 59%
Level 3: 35%-60%
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