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Q. No.Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A):
Regulation of lac operon by a repressor is referred to as negative regulation.
Reason (R):
lac operon is under the control of positive regulation as well.
In the light of the above statements, choose the most appropriate answer from the options given below :
1.
Both (A) and (R) are True but (R) is not the correct explanation of (A).
2.
Both (A) and (R) are False.
3.
Both (A) and (R) are True and (R) is the correct explanation of (A).
4.
(A) is True but (R) is False.
Subtopic: Gene Regulation: Lac Operon |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
In the light of the above statements, choose the most appropriate answer from the options given below :
| Assertion (A): | Human Genome Project was closely associated with the rapid development of a new area in biology called Bioinformatics. |
| Reason (R): | One of the greatest impacts of having the Human Genome sequence may well be enabling a radically new approach to biological research. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | Both (A) and (R) are False. |
| 4. | (A) is True but (R) is False. |
Subtopic: Human Genome Project |
Level 3: 35%-60%
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
In the light of the above statements, choose the most appropriate answer from the options given below :
| Assertion (A): | Learning about non-human organisms DNA sequences is not important for human beings. |
| Reason (R): | The Genetic code is not universal. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are False. |
| 3. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 4. | (A) is True but (R) is False. |
Subtopic: Human Genome Project | Genetic Code |
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The goals of the Human Genome Project include all the following except:
| 1. | Identify all the approximately 20,000-25,000 genes in human DNA and determine the sequences of the 3 billion chemical base pairs that make up human DNA. |
| 2. | Store the information in databases, improve tools for data analysis, and transfer related technologies to other sectors, such as industries. |
| 3. | Address the ethical, legal, and social issues (ELSI) that may arise from the project. |
| 4. | Develop technology to enable the introduction of genes into humans to manipulate their phenotypes and allow humans to demand a tailor-made gene composition for themselves. |
Subtopic: Human Genome Project |
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Which fact regarding the Human Genome Project is not correct?
| 1. | The Human Genome Project was a 13-year project coordinated by the U.S. Department of Energy and the National Institute of Health. |
| 2. | Many non-human model organisms, such as bacteria, yeast, Caenorhabditis Elegans (a free-living non-pathogenic nematode), Drosophila (the fruit fly), plants (rice and Arabidopsis), etc., have also been sequenced. |
| 3. | The sequence of chromosome 1 was completed only in May 2016 (this was the last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced). |
| 4. | The fragments were sequenced using automated DNA sequencers that worked on the principle of a method developed by Frederick Sanger. |
Subtopic: Human Genome Project |
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Identify the correctly matched pairs:
| A: | Expressed Sequence Tags | Fragments of mRNA sequences derived through single sequencing reactions performed on randomly selected clones from cDNA libraries. |
| B: | Sequence Annotations | The process of marking specific features in a DNA, RNA, or protein sequence with descriptive information about structure or function. |
| 1. | Only A | 2. | Only B |
| 3. | Both A and B | 4. | Neither A nor B |
Subtopic: Human Genome Project |
Level 3: 35%-60%
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
In the light of the above statements, choose the most appropriate answer from the options given below :
| Assertion (A): | During density gradient centrifugation, repetitive DNA are separated from bulk genomic DNA as different peaks. |
| Reason (R): | The probability of observing DNA polymorphism in non-coding sequences of DNA is higher than in the coding sequences. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are False. |
| 3. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 4. | (A) is True but (R) is False. |
Subtopic: DNA Fingerprinting |
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Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
In the light of the above statements, choose the most appropriate answer from the options given below :
| Assertion (A): | Repetitive units of DNA, micro-satellites, and mini-satellites are the basis of DNA fingerprinting. |
| Reason (R): | DNA fingerprinting is the basis of paternity testing, in cases of disputes. |
| 1. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 2. | Both (A) and (R) are False. |
| 3. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 4. | (A) is True but (R) is False. |
Subtopic: DNA Fingerprinting |
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DNA fingerprinting:
| Statement I: | involves identifying differences in some specific regions in DNA sequence called as repetitive DNA. |
| Statement II: | repetitive DNA is separated from bulk genomic DNA as different peaks during density gradient centrifugation. |
| 1. | Both Statement I and Statement II are correct but Statement II does not explain Statement I. |
| 2. | Only Statement I is correct. |
| 3. | Only Statement II is correct. |
| 4. | Both Statement I and Statement II are incorrect. |
Subtopic: DNA Fingerprinting |
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What will not be true for satellite DNA?
| 1. | Satellite DNA forms small peaks other than the bulk DNA during density gradient centrifugation. |
| 2. | Depending on the base composition (A: T rich or G: C rich), length of the segment, and the number of repetitive units, the satellite DNA is classified into many categories, such as micro-satellites, mini-satellites etc. |
| 3. | These sequences normally do not code for any proteins, but they form a large portion of the human genome. |
| 4. | These sequences do not show any polymorphism and form the basis of DNA fingerprinting. |
Subtopic: DNA Fingerprinting |
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